MULTIDIMENSIONAL CHROMATOGRAPHY HPL-GC-MS
CONICAL K2 / K2 Q12
ERRECI presents KONIK K2 Q12, the first and innovativeMULTIDIMENSIONAL chromatography(HPLC GC) fully automatic combined with Mass detector, three instruments in one solution, HPLC-Mass HRGC-Mass HPLC-HRGC-Mass.
The industry-leading Konik brand offers a system capable of interfacing HPLC/GC and/or HPLC/GC/MASSE techniques.
Specifically, the Konik K2 and K2 Q12 Multidimensional Chromatography system is composed of the following modules:
• HPLC chromatographic system, complete with detector of your choice (UV-VIS/RI/etc.), including Mass to perform LC-MS, usable as a single module or used as a pre-analytical system for multidimensional HPLC/HRGC-Mass chromatography.
• HRGCgas chromatographic systemhigh resolution, suitable for "Fast GC", complete with detector of your choice (FID/ECD/NPD/etc.), also Mass to perform GC-MS, usable as a single module, or used as a post-HPLC analytical system for multidimensional HPLC/HRGC-Mass chromatography
• Mass Detector, interfaceable with HPLC for LC-MS, with HRGC for HRGC-MS or as detector of the HPLC/HRGC/MASSA multidimensional chromatography system
• TOTAD interface for the automatic transfer of fractions of interest between HPLC and HRGC.
The modules are single and independent, and can also be purchased separately and at a later date.
You can start from the following configurations:
• HPLC, HPLC system complete with UV/RI/Fluorescence/Conductivity/etc. detector;
• LC-MS, HPLC system complete with mass detector;
• HRGC, High Resolution Gas Chromatography System suitable for “Fast GC” complete with FID/ECD/NPD/etc. detector;
• GC-MS, High Resolution Gas Chromatography System complete with Mass Detector;
• HPLC/HRGC/MASSA Multidimensional Chromatography system complete with TOTAD interface.
The advantages of the innovative system are automation and sample preparation at maximum productivity, speed and ease of use.
The K2 system allows direct injection into the system of complex matrices such as urine, plasma, blood, olive oil, mineral oils, petroleum fractions, etc.
For example, it is possible to inject olive oil samples without any pretreatment of the sample and use the HPLC system as a pre-analytical technique. Subsequently, the GC-ECD and/or GC-Mass system can be used for the analysis of pesticides or other substances of interest.
TOTAD® Thermostatted Interface allows direct and automatic analysis of the flow coming from the HPLC. The transfer to the GC is achieved using a PTV (Programmed Temperature Vaporizer) injector filled with an absorbent trap, eliminating or drastically reducing sample preparation time and cleaning operations between samples. Patented system.
MULTIDIMENSIONAL CHROMATOGRAPHY
Main advantages
- Simplified sample preparation
- Complete Automation
- Reduction of analysis times
- Reduction of solvent consumption
- It allows the rapid and easy development of new analytical methods or the improvement of already developed methods
- It ensures sample integrity by increasing the amount of recovered substance making quantification easier
- Selective or Universal Disclosure (Target and Untarget Analysis)
- Detection limits improve
- Qualitative analysis suitable for routine analyses thanks to the double retention time (HPLC and GC) and/or via the Mass Detector
- Independent use of each module (GC, HPLC, MS) for standardized analyses on these platforms, allows the addition of other modules such as ROBOKROM autosampler, headspace, P&T, SPmE, etc.
KONIKRON SOFTWARE DI GESTIONE MULTI-TASKING
Konikrom Plus Multitasking software for data acquisition, instrument control and processing for the Konik K2
• Multi-tasking, multi-tool and multi-detector software
• Management of up to 4 chromatographic systems/instruments, each of which can use up to 4 detectors
• Each instrument has an independent detection (start/stop signal)
• Eg. Konikrom Plus 4-2, means 4 instruments with two detectors for each instrument unit
• Control modules for Konik HRGC 5000 B, 4000 B; 4000 C; 5000 A; HPLC 550 A and 600; MS Q12; K2 HPLC-HRGC and Robokrom autosampler are included
• Data acquisition from the Konik MS Q12 mass spectrometer
• Integration frequency up to 100 Hz;
• 24-bit resolution with 4 inputs and 8 auxiliary outputs
• Optimized algorithm for detecting hundreds of peaks in a single run. Simple system for rereading previously acquired data.
• Storage of data, methods, calibrations and work sequences
• Data integration with 30 possible different parameters (peak width, threshold, slope, etc.) selectable at separate times and stored in an integration table
Calibration curve calculable with 6 different algorithms, using up to 20 levels; possible creation of groups, reference peaks, LOD, LOQ; unlimited number of peaks
• All the parameters described can be stored in a method file
• 12 predefined mathematical operators, 15 basis functions, Kovats Index, signal-to-noise ratio calculation, etc.
• Import/Export function in ASCII, AIA, dBase format
• Instrument control, furnace and autosampler control, lamp holder turret positioning, QC and GLP procedures
• Full support for GLP and 21 CFR Part 11 protocols; password protection, password expiration, electronic signature, audit trails, customizable user access, IQ and OQ
• MS data compression algorithm
• Complete control of the Robokrom autosampler
• Direct connection to NIST05/08 libraries, spectral search function
• The use of a Personal Computer is required
Optional Accessories available:
• OQ validation kit, SST System Suitability test, control of non-Konik HPLC systems, GPC module, PDA module.
